Modeling of the Composition of a Semisolid Propolis Preparation, and Evaluation of Its Quality
نویسندگان
چکیده
The aim of the study was to select the optimal composition of semisolid using natural materials, and to evaluate the quality of such preparation. Investigation of rheological properties, evaluation of sensory characteristics, detection and identification of phenolic acids using high-performance liquid chromatography (HPLC) were performed. The results of the rheological investigations and the study of sensory properties were evaluated, and the optimal composition of the ointment was selected: olive oil, beeswax, cocoa butter, cholesterol, soft propolis extract, and substances that improved the sensory characteristics. The base of the ointment ensures the stability of the semisolid when the active component is soft propolis extract. The results of the quantitative study by highperformance liquid chromatography identified phenolic acids and determined their amounts and showed that the predominant phenolic acids in the propolis ointment were ferulic acid and coumaric acid. The modeled hydrophobic semisolid is a stable homogenous system with positive sensory characteristics. Rezumat Studiul şi-a propus cercetarea unor formulări farmaceutice semisolide cu componente de origine naturală: ulei de masline, ceară de albine, unt de cacao, colesterol, extract de propolis. Au fost efectuate prin tehnici moderne, proprietăţile fizico-chimice ale acestui sistem. De asemenea, prin cromatografie de lichide de înaltă performanţă (HPLC) au fost identificate principalele principii active prezente în sistemul original, natural dezvoltat.
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تاریخ انتشار 2012